Use of preimplantation genetic testing for monogenic defects (PGT-M) for adult-onset conditions: an Ethics Committee opinion
Use of preimplantation genetic testing for monogenic defects (PGT-M) for adult-onset conditions: an Ethics Committee opinion
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DOI：
10.1016/j.fertnstert.2018.04.003
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发表时间：
2018-06-01
影响因子：
6.7
通讯作者：
Zweifel, Julianne
中科院分区：
文献类型：
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作者：
Daar, Judith;Benward, Jean;Zweifel, Julianne
在伦理上允许对成人发病的单基因疾病进行植入前基因检测，适用于一系列条件，包括病情严重且无安全有效干预措施的情况。委员会强烈建议有PGT-M经验的遗传咨询师为考虑此类手术的患者提供咨询。本文件取代了标题为“使用植入前遗传学诊断严重成人发病条件：委员会意见”的文件，最后发表在Fertil Steril 2013;100;54-7。(C)2018年，美国生殖医学会（American Society for Reproductive Medicine）
Preimplantation genetic testing for monogenic diseases for adult-onset conditions is ethically permissible for a range of conditions including when the condition is serious and no safe, effective interventions arc available. The Committee strongly recommends that a genetic counselor experienced with PGT-M counsel patients considering such procedures. This document replaces the document titled "Use of preimplantation genetic diagnosis for serious adult-onset conditions: a committee opinion," last published in Fertil Steril 2013;100;54-7. (C) 2018 by American Society for Reproductive Medicine.