Photochemically induced electron transfer (PET) catalyzed radical cyclization: A practical method for inducing structural changes in peptides by formation of cyclic amino acid derivatives
Photochemically induced electron transfer (PET) catalyzed radical cyclization: A practical method for inducing structural changes in peptides by formation of cyclic amino acid derivatives
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DOI：
10.1021/jo010144b
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发表时间：
2001-10-19
影响因子：
3.6
通讯作者：
Steckhan, E
中科院分区：
文献类型：
--
作者：
Jonas, M;Blechert, S;Steckhan, E
提出了一种新的不饱和氨基酸衍生物自由基环化反应。该反应是由光电子转移（PET）催化引起的，与常用的方法相比，该反应在中性介质中温和、无氧化和无毒的条件下进行。这种类型的自由基环化反应可用于肽化学，以诱导肽的结构变化。
A new radical cyclization reaction of unsaturated amino acid derivatives is presented. The reaction is induced by photoelectron transfer (PET) catalysis and proceeds, in comparison to commonly applied methods, under mild, nonoxidizing, and nontoxic conditions in neutral medium. This type of radical cyclization reaction can be used in peptide chemistry for inducing structural changes in peptides.