Supramolecular traps for highly phosphorylated inositol sources of phosphorus
Supramolecular traps for highly phosphorylated inositol sources of phosphorus
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DOI：
10.1039/c9cc09321d
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发表时间：
2020-03-18
影响因子：
4.9
通讯作者：
Bowman-James, Kristin
中科院分区：
文献类型：
--
作者：
Pramanik, Subhamay;Day, Victor W.;Bowman-James, Kristin
结构上难以捉摸的肌醇六磷酸已被捕获在两个吡啶酰胺大环化合物之间的主客体三明治中，在氢键和静电相互作用的帮助下，这些化合物在溶液中保持完整。这是关于肌醇六磷酸酯大环复合物的第一份报告，为影响全球磷循环的重要磷生物源提供了结构见解。
Structurally elusive inositol hexakisphosphates have been trapped in host-guest sandwiches between two picolinamide macrocycles that remain intact in solution, aided by hydrogen bonds and electrostatic interactions. This first report of macrocyclic complexes of inositol hexakisphosphates provides structural insight to significant biosources of phosphorus that impact the global phosphorus cycle.