Effects of Anesthetics, Sedatives, and Opioids on Ventilatory Control
Effects of Anesthetics, Sedatives, and Opioids on Ventilatory Control
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DOI：
10.1002/cphy.c100061
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发表时间：
2012-10-01
影响因子：
5.8
通讯作者：
Zuperku, Edward J.
中科院分区：
文献类型：
--
作者：
Stuth, Eckehard A. E.;Stucke, Astrid G.;Zuperku, Edward J.
本文提供了一个全面的，最新的总结，挥发性的，气体的，静脉麻醉药和阿片类激动剂对呼吸控制的影响。重点放在来自人体研究的数据上。来自其他哺乳动物物种的体内和体外数据提供了进一步的机械性见解。重点是临床相关激动剂浓度的影响和药理学研究，即不强调或排除临床上的激动剂浓度。(C)2012年美国生理学会。Comr Physiol 2：2281-2367,2012。
This article provides a comprehensive, up to date summary of the effects of volatile, gaseous, and intravenous anesthetics and opioid agonists on ventilatory control. Emphasis is placed on data from human studies. Further mechanistic insights are provided by in vivo and in vitro data from other mammalian species. The focus is on the effects of clinically relevant agonist concentrations and studies using pharmacological, that is, supraclinical agonist concentrations are de-emphasized or excluded. (C) 2012 American Physiological Society. Compr Physiol 2:2281-2367, 2012.