Brachial and femoral artery blood flow in cirrhosis: Relationship to kidney dysfunction
Brachial and femoral artery blood flow in cirrhosis: Relationship to kidney dysfunction
复制标题
肝硬化时的肱动脉和股动脉血流量：与肾功能障碍的关系
DOI：
10.1002/hep.1840170507
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发表时间：
1993
期刊：
影响因子：
13.5
通讯作者：
J. Rodés
中科院分区：
文献类型：
--
作者：
A. Maroto;P. Ginés;V. Arroyo;A. Ginès;J. Saló;J. Clària;W. Jiménez;C. Brú;F. Rivera;J. Rodés
用双多普勒超声测量了12例正常人、12例代偿性肝硬化患者和35例肝硬化合并腹水患者（8例功能性肾衰竭）的肱动脉和股总动脉血流和心输出量。本研究的目的是调查这些血管区域的小动脉血管扩张是否有助于肝硬化的高动力循环。三组肝硬化患者的心输出量显著增加，全身血管阻力显著降低。我们发现正常受试者和代偿性肝硬化患者在肱动脉（55±7 vs. 57±7 ml/min）和股动脉（353±20 vs. 310±25 ml/min）血流量方面无显著差异。非氮化肝硬化合并腹水患者臂动脉血流（40±3 ml/min）明显低于健康组和代偿组（p < 0.05）。而股动脉血流（327±25 ml/min）差异无统计学意义。肾功能衰竭患者肱动脉血流量（25±3 ml/min）和股动脉血流量（213±22 ml/min）明显减少（与其他三组相比p < 0.05）。肝硬化患者肾小球滤过率与肱动脉血流（r = 0.74, p = 0.0001）和股动脉血流（r = 0.52, p = 0.03）直接相关。这些结果表明肝硬化引起高动力循环的动脉血管扩张并不发生在肱和股血管区域。(肝脏病学17:788 1993;793)。
Brachial artery and common femoral artery blood flows and cardiac output were measured with duplex‐Doppler ultrasonography in 12 normal subjects, 12 patients with compensated cirrhosis and 35 patients with cirrhosis and ascites (8 with functional kidney failure). The aim of this study was to investigate whether arteriolar vasodilation in these vascular territories contributes to hyperdynamic circulation in cirrhosis. Cardiac output was significantly increased and systemic vascular resistance significantly reduced in the three groups of cirrhotic patients. We found no significant differences between normal subjects and compensated cirrhotic patients in brachial artery (55 ± 7 vs. 57 ± 7 ml/min) and femoral artery (353 ± 20 vs. 310 ± 25 ml/min) blood flow. Nonazotemic cirrhotic patients with ascites showed significantly lower (p < 0.05) brachial artery blood flow (40 ± 3 ml/min) than healthy subjects and compensated patients. Femoral artery blood flow (327 ± 25 ml/min), however, was not significantly different. Brachial artery (25 ± 3 ml/min) and femoral artery (213 ± 22 ml/min) blood flows were markedly reduced in the patients with kidney failure (p < 0.05 with respect to the other three groups). Glomerular filtration rate correlated directly with brachial (r = 0.74, p = 0.0001) and femoral (r = 0.52, p = 0.03) artery blood flow in the cirrhotic patients. These results indicate that the arteriolar vasodilation causing hyperdynamic circulation in cirrhosis does not take place in the brachial and femoral vascular territories. (HEPATOLOGY 1993;17:788–793.)
DOI：
10.1007/978-3-642-37078-6_144
发表时间：
2015-01-23
期刊：
PanVascular Medicine
影响因子：
--
作者：
Morales-Ruiz M;Rodríguez-Vita J;Ribera J;Jiménez W
通讯作者：
Jiménez W
影响因子：
37.8
作者：
LEWIS, JF;KUO, LC;QUINONES, MA
通讯作者：
QUINONES, MA