Beneficial effect of 15% azelaic acid cream on acne vulgaris
Beneficial effect of 15% azelaic acid cream on acne vulgaris
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有益%20效果%20of%2015%%20壬二酸%20酸%20霜%20on%20痤疮%20寻常
DOI：
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发表时间：
1983
影响因子：
10.3
通讯作者：
G. Zina
中科院分区：
文献类型：
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作者：
M. Nazzaro;S. Passi;Mauro Picardo;A. Breathnach;R. Clayton;G. Zina
用壬二酸（15%）乳膏治疗黄褐斑的患者报告治疗区域内的痤疮病变同时改善。这促使人们对其在没有黄褐斑的痤疮病例中的作用进行了公开研究。100例寻常痤疮患者接受了3-9个月的治疗，每天两次使用该药膏，每例均有显著改善。
Patients treated with azelaic acid (15%) cream for chloasma reported simultaneous improvement of acne lesions within the treated areas. This prompted an open study of its effect in cases of acne without chloasma. One hundred patients with acne vulgaris were treated for 3–9 months by twice‐daily application of the cream with significant improvement in every case.