Combination of two-dimensional shear wave elastography with ultrasound breast imaging reporting and data system in the diagnosis of breast lesions: a new method to increase the diagnostic performance
Combination of two-dimensional shear wave elastography with ultrasound breast imaging reporting and data system in the diagnosis of breast lesions: a new method to increase the diagnostic performance
复制标题
二维剪切波弹性成像与超声乳腺成像报告和数据系统相结合用于乳腺病变诊断：提高诊断性能的新方法
DOI：
10.1007/s00330-015-4163-8
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发表时间：
2016-09-01
影响因子：
5.9
通讯作者：
Zhang, Kun
中科院分区：
文献类型：
--
作者：
Li, Dan-Dan;Xu, Hui-Xiong;Zhang, Kun
目的评价一种新的二维剪切波弹性成像方法的诊断性能（即虚拟触摸成像量化，VTIQ）和超声（US）乳腺成像报告和数据系统（BI-RADS）在乳腺病变鉴别诊断中的应用。材料和方法从2014年9月至2014年12月，本研究入组了276例患者，共296处经病理证实的乳腺病变。传统的美国图像由两个独立的读者解释。评价BI-RADS和BI-RADS与VTIQ联合应用的诊断性能，包括受试者工作特征曲线下面积（AUROC）、敏感性和特异性。观察员的一致性也evaluated.ResultsPathologically，212乳腺病变良性和84恶性。与单独BI-RADS相比，联合方法对两个读片者的AUROC和特异性显著增加（AUROC：读片者1中0.862 vs. 0.693，读片者2中0.861 vs. 0.730;特异性：读片者1中91.5% vs. 38.7%，读片者2中94.8% vs. 47.2%;均P <0.05）。结论VTIQ和BI-RADS联合应用对乳腺病变的诊断性能优于BI-RADS单独应用。要点·常规超声和弹性成像联合应用能更有效地鉴别乳腺癌。常规超声和弹性成像的结合提高了观察者的一致性。·BI-RADS权重大于2D-SWE，恶性概率增加。
ObjectivesTo evaluate the diagnostic performance of a new method of combined two-dimensional shear wave elastography (i.e. virtual touch imaging quantification, VTIQ) and ultrasound (US) Breast Imaging Reporting and Data System (BI-RADS) in the differential diagnosis of breast lesions.Materials and methodsFrom September 2014 to December 2014, 276 patients with 296 pathologically proven breast lesions were enrolled in this study. The conventional US images were interpreted by two independent readers. The diagnosis performances of BI-RADS and combined BI-RADS and VTIQ were evaluated, including the area under the receiver operating characteristic curve (AUROC), sensitivity and specificity. Observer consistency was also evaluated.ResultsPathologically, 212 breast lesions were benign and 84 were malignant. Compared with BI-RADS alone, the AUROCs and specificities of the combined method for both readers increased significantly (AUROC: 0.862 vs. 0.693 in reader 1, 0.861 vs. 0.730 in reader 2; specificity: 91.5 % vs. 38.7 % in reader 1, 94.8 % vs. 47.2 % in reader 2; allP< .05). The Kappa value between the two readers for BI-RADS assessment was 0.614, and 0.796 for the combined method.ConclusionThe combined VTIQ and BI-RADS had a better diagnostic performance in the diagnosis of breast lesions in comparison with BI-RADS alone.Key Points•Combination of conventional ultrasound and elastography distinguishes breast cancers more effectively.•Combination of conventional ultrasound and elastography increases observer consistency.•BI-RADS weights more than the 2D-SWE with an increase in malignancy probability.