[Diagnostic efficiency of sonographic findings of thyroid nodules in the detection of malignancy].
[Diagnostic efficiency of sonographic findings of thyroid nodules in the detection of malignancy].
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DOI：
10.1016/j.endonu.2010.03.006
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发表时间：
2010-06-01
期刊：
影响因子：
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通讯作者：
Tenias Burillo, Jose M
中科院分区：
文献类型：
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作者：
Gonzalez-Gonzalez, Abel;Mate Valdezate, Alberto;Tenias Burillo, Jose M
目的：通过与细针吸取活检(FNAB)结果比较，评价超声对甲状腺结节大小、微钙化及回声的诊断价值。方法：分析341例甲状腺结节的细胞学及声像图特征。结果：341例甲状腺结节中，25.5%的细针吸取细胞学检查不充分，65.1%为良性，7.9%为可疑或恶性。直径小于15 mm的结节标本不足的比例明显较大，但恶性细胞学的比例也较高(11.1vs2.8%：P=0.04)。小于10 mm的结节中样本不足的比例为66.7%，未发现恶性肿瘤。一个值得注意的发现是，在高回声和无回声的结节中没有可疑或恶性的FNAB。相反，最常见的与恶性肿瘤相关的回声特征是低回声，尽管作为一个整体，回声与恶性肿瘤并不显著相关(p=0.313)。大多数有微钙化的结节(6/10)是恶性的，而239个无钙化的结节中有4个(1.7%)是恶性的(p
OBJECTIVE: To evaluate the diagnostic efficiency of sonographic findings (nodule size, the presence of microcalcifications and echogenicity) compared with the results of fine-needle aspiration biopsy (FNAB) of thyroid nodules.METHODS: The results of cytology and the ultrasound characteristics of 341 thyroid nodules were analyzed.RESULTS: A total of 25.5% of the FNAB were inadequate, 65.1% were benign and 7.9% were suspicious or malignant. The percentage of inadequate samples was clearly larger in nodules smaller that 15 mm but that of malignant cytologies was also larger in this group of nodules (11.1 versus 2.8%: p=0.04). The percentage of inadequate samples among nodules smaller than 10 mm was 66.7% and no malignancies were detected. A notable finding was the absence of suspicious or malignant FNAB in hyperechogenic and anechogenic nodules. In contrast, the echogenic feature most frequently associated with malignancy was hypoechogenicity, although echogenicity, as a whole, was not significantly associated with malignancy (p=0.313). Most cases with microcalcifications (6 of 10) were malignant compared with four of the 239 nodules (1.7%) without calcifications (p