Microbiology of liver and spleen abscesses
Microbiology of liver and spleen abscesses
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DOI：
10.1099/00222615-47-12-1075
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发表时间：
1998-12-01
影响因子：
3
通讯作者：
Frazier, EH
中科院分区：
文献类型：
--
作者：
Brook, I;Frazier, EH
为研究肝脾脓肿的需氧菌群和厌氧菌群，并将其与感染的诱因、潜在原因和途径相关联，对1970~1990年间收治的48例肝脓肿和29例脾脓肿的临床和实验室资料进行了回顾分析。肝脓肿共检出116株(2.4株/标本)，需氧和兼性菌株43株(0.9株/标本)，厌氧或微需氧链球菌73株(1.5株/标本)。需氧菌12例(25%)，厌氧菌8例(17%)，需氧厌氧混合菌28例(58%)，多菌感染38例(79%)。需氧菌和兼性菌以大肠埃希菌(11株)、D群链球菌(8株)、肺炎克雷伯菌(5株)和金黄色葡萄球菌(4株)为主。厌氧菌以消化链霉菌为主。(18株)、拟杆菌属(Bacteroids spp.)(13)、梭杆菌属(Fusbacterium spp.)(10)、梭菌属(Clostridium spp.)(10)和普雷沃特氏菌(Prevoella spp.)(4)。共分离出嗜氧微嗜氧链球菌12株。创伤与金黄色葡萄球菌和β-溶血性链球菌有关，D、II类链球菌。肺炎杆菌和梭状芽胞杆菌。胆道疾病；类杆菌属。和梭菌属(Clostridium spp.)患有结肠病。在脾脓肿中共检出56株(1.9株/标本)，其中需氧和兼性菌株23株(0.8株/标本)，厌氧或微需氧链球菌31株(1.1株/标本)，白色念珠菌2株。需氧菌9例(31%)，厌氧菌8例(28%)，需氧厌氧混合菌10例(34%)，白色念珠菌2例(7%)，多菌感染16例(55%)。需氧菌和兼性菌主要为大肠埃希菌(5株)、奇异变形杆菌(3株)、D群链球菌(3株)、肺炎克雷伯菌(3株)和金黄色葡萄球菌(4株)。厌氧菌以消化链球菌为主。(11株)、拟杆菌属(Bacteroids spp.)(5)、梭杆菌属(Fusbacterium spp.)(3)和梭状芽孢杆菌。(3)。金黄色葡萄球菌、肺炎克雷伯菌和D群链球菌与心内膜炎有关，大肠埃希菌合并尿路和腹部感染，类杆菌属。和梭菌属(Clostridium spp.)合并腹部感染和梭菌属。患有呼吸道感染。
To study the aerobic and anaerobic microbiology of liver and spleen abscesses and correlate the results with predisposing factors, potential causes and routes of infection, clinical and laboratory data of 48 patients with liver abscesses and 29 with spleen abscesses treated between 1970 and 1990 were reviewed retrospectively. In liver abscesses, a total of 116 isolates (2.4 isolates/specimen) was obtained; 43 were aerobic and facultative species (0.9 isolates/specimen) and 73 were anaerobic species or microaerophilic streptococci (1.5 isolates/specimen). Aerobic bacteria only were isolated from 12 (25%) abscesses, anaerobic bacteria only from eight (17%), and mixed aerobic and anaerobic bacteria from 28 (58%); polymicrobial infection was present in 38 (79%). The predominant aerobic and facultative isolates were Escherichia coli (11 isolates), Streptococcus group D (8), Klebsiella pneumonia (5) and Staphylococcus aureus (4). The predominant anaerobes were Peptostreptacoccus spp. (18 isolates), Bacteroides spp. (13), Fusobacterium spp. (10), Clostridium spp. (10) and Prevotella spp. (4). There were 12 isolates of microaerophilic streptococci. S. aureus and beta-haemolytic streptococci were associated with trauma; Streptococcus group D, Ii. pneumoniae and Clostridium spp. with biliary disease; and Bacteroides spp. and Clostridium spp. with colonic disease. In splenic abscesses, a total of 56 isolates (1.9 isolates/specimen) was obtained; 23 were aerobic and facultative species (0.8 isolates/specimen), 31 were anaerobic species or micro-aerophilic streptococci (1.1 isolates/specimen) and two were Candida albicans. Aerobic bacteria only were isolated from nine (31%) abscesses, anaerobic bacteria from eight (28%), mixed aerobic and anaerobic bacteria from 10 (34%) and C. albicans in two (7%); polymicrobial infection was present in 16 (55%). The predominant aerobic and facultative isolates were E. coli (5 isolates), Proteus mirabilis (3), Streptococcus group D (3), K. pneumoniae (3) and S. aureus (4). The predominant anaerobes were Peptostreptococcus spp. (11 isolates), Bacteroides spp. (5), Fusobacterium spp. (3) and Clostridium spp. (3). S. aureus, K. pneumoniae and Streptococcus group D were associated with endocarditis, E. coli with urinary tract and abdominal infection, Bacteroides spp. and Clostridium spp. with abdominal infection and Fusobacterium spp. with respiratory infection.