Limb regeneration in Xenopus laevis froglet

Limb regeneration in Xenopus laevis froglet
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DOI:
10.1100/tsw.2006.325
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发表时间:
2006-12-01
影响因子:
--
通讯作者:
Tamura, Koji
Tamura, Koji
中科院分区:
其他
文献类型:
--
作者:
Suzuki, Makoto;Yakushiji, Nayuta;Tamura, Koji

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两栖动物的肢体再生是一种典型的表型发育过程。这种类型的器官再生,其中称为“芽基”的未分化细胞的质量增殖以恢复截肢器官的丢失部分,与例如在Hydra中观察到的形态反应不同,其中预先存在的细胞和组织的重排主要有助于再生。与有尾目两栖动物的完全肢体再生相反,无尾两栖动物非洲爪蟾的肢体再生受到限制。在这篇综述中的一些方面有关非洲爪蟾的成年肢体再生,我们建议,在成年非洲爪蟾,这是模式/组织缺陷,也代表epimorphosis的肢体再生。
Limb regeneration in amphibians is a representative process of epimorphosis. This type of organ regeneration, in which a mass of undifferentiated cells referred to as the "blastema" proliferate to restore the lost part of the amputated organ, is distinct from morphallaxis as observed, for instance, in Hydra, in which rearrangement of pre-existing cells and tissues mainly contribute to regeneration. In contrast to complete limb regeneration in urodele amphibians, limb regeneration in Xenopus, an anuran amphibian, is restricted. In this review of some aspects regarding adult limb regeneration in Xenopus laevis, we suggest that limb regeneration in adult Xenopus, which is pattern/tissue deficient, also represents epimorphosis.