Nonspecific ulcer of the colon.
Nonspecific ulcer of the colon.
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结肠非特异性溃疡。
DOI：
10.1001/archsurg.1968.01340010163022
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发表时间：
1968
影响因子：
--
通讯作者：
W. Ballinger
中科院分区：
文献类型：
--
作者：
W. Smithwick;R. Anderson;W. Ballinger
发生在大肠内的非肿瘤性溃疡通常由病原菌或寄生虫引起，或与明确的炎症性疾病（如溃疡性结肠炎）相关。然而，偶尔也会遇到孤立性结肠溃疡的病人，在这些病人中找不到病原体，因为这些病人通常在腹部灾难中出现穿孔、出血或部分大肠梗阻，外科医生可能被迫紧急处理。在这些情况下，癌症的错误诊断可能会导致比实际需要更广泛的程序。非特异性结肠溃疡，没有明显的病因，多年来一直被认为是一个独立的临床实体。由于诊断通常是在排除结肠溃疡的特殊原因后作出的，因此很少在术前作出诊断，最好的情况下，
NONNEOPLASTIC ulceration occurring within the large intestine is usually produced by pathogenic bacteria or parasites or occurs in association with a well-defined inflammatory disorder such as ulcerative colitis. Occasionally, however, patients with isolated colon ulcers are encountered in whom no etiologic agent can be found. Because these patients are often seen initially in the midst of an abdominal catastrophe with perforation, hemorrhage, or partial large bowel obstruction, the surgeon may be forced to deal with them on an urgent basis. Under these conditions an erroneous diagnosis of carcinoma may lead to the performance of a more extensive procedure than is actually required. Nonspecific ulceration of the colon, with no obvious etiologic agent, has been recognized as a discrete clinical entity for many years. 1 Since the diagnosis is usually made by excluding specific causes of ulceration of the colon, it is seldom made preoperatively and, at best, can