Echocardiographic dimensions in borderline and sustained hypertension.
Echocardiographic dimensions in borderline and sustained hypertension.
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临界和持续性高血压的超声心动图尺寸。
DOI：
10.1016/0002-9149(79)90224-8
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发表时间：
1979
期刊：
影响因子：
--
通讯作者：
A. Simon
中科院分区：
文献类型：
--
作者：
M. E. Safar;J.P. Lehner;M.I. Vincent;M. T. Plainfosse;A. Simon
本文测定了42例临界高血压和22例持续性高血压患者的超声心动图参数和血流动力学指标，并与33例正常人的结果进行了比较。临界高血压患者室间隔厚度明显增加（P< 0.001），而后壁厚度在正常范围内。IVS PW比值明显升高（P< 0.001），与心脏指数呈负相关（P< 0.01），与射血前期呈正相关（P< 0.01）。持续性高血压患者心肌呈对称性肥厚，IVS PW比值与舒张压呈显著正相关（P< 0.05）。结果提示：（1）持续性高血压时，对称性心肌肥厚继发于压力负荷的进行性增加;（2）临界性高血压时，不对称性心肌肥厚与血压水平无直接关系，可能与交感神经系统异常有关。
Echocardiographic dimensions and hemodynamic indexes were determined in 42 patients with borderline hypertension and in 22 with sustained hypertension and the results were compared with findings in 33 normal subjects. In patients with borderline hypertension the thickness of the interventricular septum (IVS) was significantly increased (P< 0.001), whereas the posterior wall (PW) thickness remained within normal range. The IVS PW ratio was significantly elevated (P< 0.001) and was correlated negatively with the cardiac index (P< 0.01) and positively with the preejection period (P< 0.01). In patients with sustained hypertension a symmetric cardiac hypertrophy was observed, and there was a significant positive correlation between the IVS PW ratio and diastolic pressure (P< 0.05). The study suggested that (1) in sustained hypertension the symmetric cardiac hypertrophy was secondary to a progressive increase in pressure load, whereas (2) in borderline hypertension the asymmetric cardiac hypertrophy could not be directly related to the level of blood pressure and was probably associated with abnormalities of the sympathetic nervous system.