Prevalence of bacterial resistance to quinolones and other antimicrobials among avian Escherichia coli strains isolated from septicemic and healthy chickens in Spain

Prevalence of bacterial resistance to quinolones and other antimicrobials among avian Escherichia coli strains isolated from septicemic and healthy chickens in Spain
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DOI:
10.1128/jcm.35.8.2184-2185.1997
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发表时间:
1997-08-01
影响因子:
9.4
通讯作者:
Blanco, J
Blanco, J
中科院分区:
医学2区
文献类型:
--
作者:
Blanco, JE;Blanco, M;Blanco, J

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抗微生物治疗是减少家禽业中由大肠杆菌感染(大肠杆菌病)引起的巨大损失的重要工具。然而,对现有抗菌剂的耐药性是普遍存在的,并引起了家禽兽医的关注。在西班牙分离的468株禽大肠杆菌菌株的耐药性试验显示,对甲氧苄啶-磺胺甲恶唑(67%)和新型氟喹诺酮类(13 - 24%)具有非常高的耐药性,由于这些抗菌药物可能会引起与人类肠道病原体的交叉耐药性,因此强烈建议在兽医中谨慎使用。
Antimicrobial therapy is an important tool in reducing the enormous losses in the poultry industry caused by Escherichia coli infections (colibacillosis). However, resistance to existing antimicrobials is widespread and of concern to poultry veterinarians. Antimicrobial resistance testing of 468 avian E, coli strains isolated in Spain showed very high levels of resistance to trimethoprim-sulfamethoxazole (67%) and the new fluoroquinolones (13 to 24%), As these antimicrobial agents may cause cross-resistance with human enteric pathogens, prudent use of them in veterinary medicine is highly recommended.