EFFECT OF FOOD AND ACTIVITY ON THE REPRODUCIBILITY OF ISOTOPIC GFR ESTIMATION
EFFECT OF FOOD AND ACTIVITY ON THE REPRODUCIBILITY OF ISOTOPIC GFR ESTIMATION
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DOI：
10.1097/00006231-199010000-00005
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发表时间：
1990-10-01
影响因子：
1.5
通讯作者：
WALLER, DG
中科院分区：
文献类型：
--
作者：
WILKINSON, J;FLEMING, JS;WALLER, DG
研究了26例患者在禁食和静息条件下99Tcm DTPA血浆清除率的再现性。肾小球滤过率（GRF）范围为11-103 ml min-1的患者重复测量的变异系数为8%。早餐含有670千卡和31克蛋白质后的平均GFR从40.7 +-显著增加。28.1 ml min-1至43.6 +-。30.8毫升min-1至43.6 +-。30.8 ml min-1。当禁食但允许自由运动时，GFR没有一致的趋势，但重复估计的变异系数显著增加到12.1%。建议在禁食或清淡饮食后进行常规GFR测量，并限制活动。
The reproducibility of the plasma clearance of 99Tcm DTPA was studied in 26 patients under standardized conditions with the subject fasting and at rest. The coefficient of variation of duplicate measurements in patients with glomerular filtration rates (GRF''s) ranging from 11-103 ml min-1 was 8%. Mean GFR following a breakfast containing 670 kcal and 31 g protein was increased significantly from 40.7 .+-. 28.1 ml min-1 to 43.6 .+-. 30.8 ml min-1 to 43.6 .+-. 30.8 ml min-1. When fasted but permitted free exercise there was no consistent trend in GFR but the coefficient of variation of duplicate estimates increased significantly to 12.1%. It is recommended that routine GFR measurement should be carried out fasting or following a light diet with restricted activity.