Studies on the epidemiology of bluetongue virus in China
Studies on the epidemiology of bluetongue virus in China
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DOI：
10.1017/s0950268801006525
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发表时间：
2002-04-01
影响因子：
4.2
通讯作者：
Hunt, NT
中科院分区：
文献类型：
--
作者：
Kirkland, PD;Zhang, N;Hunt, NT
1995年至1997年，在中华人民共和国云南省的五个中心建立了大型反刍动物的哨兵群。应用敏感的抗原捕获ELISA，以促进病毒分离程序，导致108株蓝舌病（BLU）病毒的分离。分离的血清型包括1、2、3、4、9、11、12、15、16、21和23型。病毒传播发生在1-3个月的时间内，在四个阳性地点的每一个，使全省的总BLU病毒传播期为5个月，从6月初至11月初。7月和8月传播率最高。个体动物的病毒血症持续时间从1周到7周不等，每种血清型的平均值计算为6到20天。本研究首次利用哨点群对BLU在中国的流行病学进行了详细的调查。
Sentinel herds of large ruminants were established at five centres in Yunnan Province, Peoples Republic of China, between 1995 and 1997. The application of a sensitive antigen capture ELISA to facilitate virus isolation procedures led to the isolation of 108 strains of bluetongue (BLU) virus. Serotypes isolated included types 1, 2, 3, 4, 9, 11, 12, 15, 16, 21 and 23. Virus transmission occurred over a period of 1-3 months at each of the four positive sites, giving an overall BLU virus transmission period for the province of 5 months, from early June to early November. The greatest level of transmission took place in July and August. The duration of viraemia in individual animals varied from 1 to 7 weeks, with a mean calculated for each serotype between 6 and 20 days. The study represents the first detailed investigation of the epidemiology of BLU in China utilizing sentinel herds.