A membranous spindle matrix orchestrates cell division.
A membranous spindle matrix orchestrates cell division.
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DOI：
10.1038/nrm2919
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发表时间：
2010-07
期刊：
影响因子：
--
通讯作者：
Zheng Y
中科院分区：
文献类型：
--
作者：
Zheng Y
真核细胞分裂使用形态上不同形式的有丝分裂，称为开放、部分开放和闭合有丝分裂，用于准确的染色体分离和其他细胞组分如内膜和细胞命运决定子的适当分配。最近的研究表明，纺锤体基质提供了一个保守的策略，以协调遗传物质的分离和所有三种形式的有丝分裂中的其余细胞内容物的分配。
Eukaryotic cell division uses morphologically different forms of mitosis, referred to as open, partially open and closed mitosis, for accurate chromosome segregation and proper partitioning of other cellular components such as endomembranes and cell fate determinants. Recent studies suggest that the spindle matrix provides a conserved strategy to coordinate the segregation of genetic material and the partitioning of the rest of the cellular contents in all three forms of mitosis.