DASH and Mediterranean-type Dietary Patterns to Maintain Cognitive Health.
DASH and Mediterranean-type Dietary Patterns to Maintain Cognitive Health.
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DOI：
10.1007/s13668-013-0070-2
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发表时间：
2014-03-01
影响因子：
4.9
通讯作者：
Tangney CC
中科院分区：
文献类型：
--
作者：
Tangney CC
越来越多的人认为，随着美国人口老龄化，近三分之一的人将经历中风，痴呆症甚至两者兼而有之。因此，对饮食在保持认知能力方面可能发挥的作用的兴趣继续增长，特别是在缺乏真正有效的痴呆症治疗方法的情况下，其中阿尔茨海默病（AD）是最常见的形式。本综述的目的是研究两种先验的饮食模式是否会影响认知能力下降或痴呆症的发病率。来自那些死于AD或轻度认知障碍（MCI）或无认知障碍的患者的神经病理学报告的证据表明，AD的病理学标志--淀粉样蛋白沉积和缠结的存在沿着血管病变。高血压和中风与痴呆症的发生密切相关。因此，旨在预防或减少心血管风险因素，疾病或疾病的生活方式方法也可能为大脑健康提供额外的好处。
There is growing consensus that as the US population ages, nearly a third will experience stroke, dementia or even both. Thus, interest in the role that diet may play in preserving cognitive abilities continues to grow especially in absence of truly effective treatments for dementia, of which Alzheimer's disease (AD) is the most common form. The purpose of this review is to examine whether two a priori dietary patterns influence the rate of cognitive decline or the onset of dementia. Evidence from neuropathology reports of those who have died with AD or with mild cognitive impairment (MCI) or without cognitive impairment suggests that often the pathological hallmarks of AD---amyloid deposition and presence of tangles are present along with vascular lesions. Hypertension and stroke are strongly associated with incident dementia. Thus, it is possible that lifestyle approaches designed to prevent or reduce cardiovascular risk factors, conditions or diseases may also provide added benefits for brain health.