Reusable urine glucose sensor based on functionalized graphene oxide conjugated Au electrode with protective layers.
Reusable urine glucose sensor based on functionalized graphene oxide conjugated Au electrode with protective layers.
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DOI：
10.1016/j.btre.2014.06.003
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发表时间：
2014-09
期刊：
影响因子：
--
通讯作者：
Lee MH
中科院分区：
文献类型：
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作者：
Kim HY;Jang KJ;Veerapandian M;Kim HC;Seo YT;Lee KN;Lee MH
开发了一种基于电化学的系统，该系统具有涂覆在官能化氧化石墨烯Au电极上的多层，以更稳定的方式测量尿液中的葡萄糖浓度。制备了两种类型的金印刷电路板，并通过化学吸附将氧化石墨烯固定在其表面。在电极表面均匀地涂覆了由几种聚合物组成的多层膜。该装置对葡萄糖表现出更高的电化学响应，在尿液中存在干扰物质的情况下具有更大的电阻率，并且比传统装置具有更长时间的持久稳定性。在该层的固定过程中，根据溶液的顺序和比例评估了电流水平的效率。然后还使用高血糖临床样品评估制造的电极，并与用市售葡萄糖仪测量的血糖模式进行比较。我们的研究结果表明，不仅是他们的模式相似，但这种相似性是很好的相关性。
An electrochemical based system with multiple layers coated on a functionalized graphene oxide Au electrode was developed to measure glucose concentration in urine in a more stable way. Two types of gold printed circuit boards were fabricated and graphene oxide was immobilized on their surface by chemical adsorption. Multiple layers, composed of a couple of polymers, were uniformly coated on the surface electrode. This device exhibited higher electrochemical responses against glucose, a greater resistivity in the presence of interferential substances in urine, and durable stabilities for longer periods of time than conventional units. The efficiency in current level according to the order and ratio of solution was evaluated during the immobilization of the layer. The fabricated electrodes were then also evaluated using hyperglycemic clinical samples and compared with the patterns of blood glucose measured with commercially available glucose meters. Our findings show that not only was their pattern similar but this similarity is well correlated.