Variations in running activity and enzymatic adaptations in voluntary running rats.
Variations in running activity and enzymatic adaptations in voluntary running rats.
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自愿跑步大鼠跑步活动和酶适应的变化。
DOI：
10.1152/jappl.1989.66.3.1250
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发表时间：
1989
期刊：
影响因子：
--
通讯作者：
Mondon,CE
中科院分区：
文献类型：
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作者：
Rodnick,KJ;Reaven,GM;Haskell,WL;Sims,CR;Mondon,CE
在运动轮笼中训练6周后，研究了雄性Sprague-Dawley大鼠的跑步行为和与自愿跑步活动相关的氧化和糖酵解活动的生化标志物。24小时的跑步活动记录被用来量化个人跑步比赛的次数，他们的持续时间和跑步速度，以及每天的跑步距离。然后，我们根据最后3周训练期间每天的平均跑步距离建立了三种自愿跑步活动类别：低活动跑步者平均每天2-5公里，中等跑步者6-9公里/天，高跑步者超过11公里/天。每组均表现出间歇性夜间跑步模式，强度相对较高，所有组的平均跑步速度相似（平均约45 m/min）。每天总跑步距离的差异是个人跑步次数和持续时间变化的结果。具体而言，高跑步者（n = 7）每24小时有206 +/- 30次个人跑步，每次持续87 +/- 7 s;中等跑步者（n = 7）221 +/- 22次跑步，持续47 +/- 5 s;低跑步者（n = 7）113 +/- 7次，每次持续40 +/- 7 s。尽管所有跑步者的食物和水摄入量增加，但与久坐不动的对照组大鼠相比，自愿跑步降低了体重增加的速度。此外，饮酒活动在时间上与跑步时间相关。（250字处删节）
The running behavior and biochemical markers of oxidative and glycolytic activities associated with voluntary running activity were studied in male Sprague-Dawley rats after 6 wk of training in exercise wheel cages. Twenty-four-hour recordings of running activity were used to quantify the number of individual running bouts, their duration and running speed, and the distance run per day. We then established three categories of voluntary running activity based on the mean distance run per day during the last 3 wk of training: low-activity runners averaged 2–5 km/day, medium runners 6–9 km/day, and high runners greater than 11 km/day. Each group demonstrated an intermittent, nocturnal running pattern, at relatively high intensities, with a similar mean running speed for all groups (avg approximately 45 m/min). Differences in total distance run per day were the result of variations in both the number and duration of individual running bouts. Specifically, high runners (n = 7) had 206 +/- 30 individual running bouts per 24 h, each lasting 87 +/- 7 s; medium runners (n = 7) 221 +/- 22 running bouts, lasting 47 +/- 5 s; and low runners (n = 7) 113 +/- 7 bouts, each lasting 40 +/- 7 s. Voluntary running depressed the rate of body weight gain compared with sedentary control rats, despite an increased food and water intake for all runners. Furthermore, drinking activity was temporally associated with running periods.(ABSTRACT TRUNCATED AT 250 WORDS)