Hop-on hop-off: Polysomes take a tour of the cell on endosomes
Hop-on hop-off: Polysomes take a tour of the cell on endosomes
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随上随下：多核糖体在内体上游览细胞
作者：
I. Palacios
核糖体从细胞核输出后，需要分布在整个细胞中，以便蛋白质合成即使在远处也能发生。在真菌黑穗病菌（Ustilago maydis）的细长菌丝细胞中，Higuchi等人（2014）。[j]细胞生物学。http://dx.doi.org/10.1083/jcb.201307164)现在证明了多聚体与早期内体相关，这些内体经历了运动蛋白3和动力蛋白依赖的远程运动。早期核内体的双向运动随机分布多体，这可能保证翻译机制在整个细胞内的均匀分布。
After export from the nucleus, ribosomes need to be distributed throughout the entire cell so that protein synthesis can occur even at distant sites. In the elongated hyphal cell of the fungus Ustilago maydis, Higuchi et al. (2014. J. Cell Biol. http://dx.doi.org/10.1083/jcb.201307164) now demonstrate that polysomes associate with early endosomes that undergo kinesin 3– and dynein-dependent long-range motility. The bidirectional movement of early endosomes randomly distributes polysomes, which may ensure the even distribution of the translation machinery across the entire cell.
影响因子：
4
作者：
Baumann, Sebastian;Pohlmann, Thomas;Feldbruegge, Michael
通讯作者：
Feldbruegge, Michael
影响因子：
5.4
作者：
Egan MJ;McClintock MA;Reck-Peterson SL
通讯作者：
Reck-Peterson SL