Phase diagram of a ternary mixture of cholesterol and saturated and unsaturated lipids calculated from a microscopic model
Phase diagram of a ternary mixture of cholesterol and saturated and unsaturated lipids calculated from a microscopic model
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DOI：
10.1103/physrevlett.96.098101
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发表时间：
2006-03-10
影响因子：
8.6
通讯作者：
Schick, M
中科院分区：
文献类型：
--
作者：
Elliott, R;Szleifer, I;Schick, M
We employ a molecular model to study a ternary mixture of saturated lipid, with tails of 16 carbons, a monounsaturated lipid with tails of 18 carbons, and cholesterol. The model, solved within mean-field theory, produces several forms of phase diagrams depending upon the relative strengths of interactions, but only one that shows the coexistence of two liquid phases observed in experiment. The lipids in the phase rich in cholesterol are more ordered than those in the other. The binary cholesterol, saturated lipid system also exhibits liquid, liquid coexistence.
