Insights from nanotechnology in COVID-19 treatment.
Insights from nanotechnology in COVID-19 treatment.
复制标题
纳米技术在COVID-19治疗中的见解。
DOI:
10.1016/j.nantod.2020.101019
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发表时间:
2021-03
期刊:
影响因子:
17.4
通讯作者:
Tao W
中科院分区:
文献类型:
--
作者:
Tang Z;Zhang X;Shu Y;Guo M;Zhang H;Tao W
In just a few months, SARS-CoV-2 and the disease it causes, COVID-19, created a worldwide pandemic. Virologists, biologists, pharmacists, materials scientists, and clinicians are collaborating to develop efficient treatment strategies. Overall, in addition to the use of clinical equipment to assist patient rehabilitation, antiviral drugs and vaccines are the areas of greatest focus. Given the physical size of SARS-CoV-2 and the vaccine delivery platforms currently in clinical trials, the relevance of nanotechnology is clear, and previous antiviral research using nanomaterials also supports this connection. Herein we briefly summarize current representative strategies regarding nanomaterials in antiviral research. We focus specifically on SARS-CoV-2 and the detailed role that nanotechnology can play in addressing this pandemic, including i) using FDA-approved nanomaterials for drug/vaccine delivery, including further exploration of the inhalation pathway; ii) introducing promising nanomaterials currently in clinical trials for drug/vaccine delivery; iii) designing novel biocompatible nanomaterials to combat the virus via interfering in its life cycle; and iv) promoting the utilization of nanomaterials in pneumonia treatment.
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