Extra cytoplasmic function σ factor activation.
Extra cytoplasmic function σ factor activation.
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DOI:
10.1016/j.mib.2012.01.001
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发表时间:
2012-04
影响因子:
5.4
通讯作者:
Ellermeier, Craig D.
中科院分区:
文献类型:
--
作者:
Ho, Theresa D.;Ellermeier, Craig D.
The bacterial cell envelope is essential for cell viability and is a target for numerous antibiotics and host immune defenses. Thus bacteria must sense and respond to damage to the cell envelope. Many bacteria utilize alternative σ factors such as Extracytoplasmic function (ECF) σ factors to respond to cell envelope stress. Although ECF σ factors are utilized by both Gram negative and Gram positive bacteria to respond to cell envelope stress, the mechanisms of sensing differ. In this review, we examine the events and proteins which are required for activation of two model Extracytoplasmic function σ factors, σE in E. coli and σW in B. subtilis.
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