CONTROL OF TRANSCRIPTION FACTORS BY SIGNAL TRANSDUCTION PATHWAYS - THE BEGINNING OF THE END
CONTROL OF TRANSCRIPTION FACTORS BY SIGNAL TRANSDUCTION PATHWAYS - THE BEGINNING OF THE END
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DOI：
10.1016/0968-0004(92)90012-x
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发表时间：
1992-10-01
影响因子：
13.8
通讯作者：
SMEAL, T
中科院分区：
文献类型：
--
作者：
KARIN, M;SMEAL, T
信号转导通路通过调节核转录因子的活性来调节基因的表达。描述了控制两组序列特异性转录因子AP-1和CREB/ATF蛋白活性的机制。这些因素作为一个范例，解释了调控信息从细胞表面到细胞核的转移。
Signal transduction pathways regulate gene expression by modulating the activity of nuclear transcription factors. The mechanisms that control the activity of two groups of sequence-specific transcription factors, the AP-1 and CREB/ATF proteins, are described. These factors serve as a paradigm explaining the transfer of regulatory information from the cell surface to the nucleus.