Forest Fire Smoke Exposures and Out-of-Hospital Cardiac Arrests in Melbourne, Australia: A Case-Crossover Study
Forest Fire Smoke Exposures and Out-of-Hospital Cardiac Arrests in Melbourne, Australia: A Case-Crossover Study
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DOI：
10.1289/ehp.1408436
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发表时间：
2015-10-01
影响因子：
10.4
通讯作者：
Tonkin, Andrew M.
中科院分区：
文献类型：
--
作者：
Dennekamp, Martine;Straney, Lahn D.;Tonkin, Andrew M.
背景资料：数百万人可能会暴露在森林火灾产生的烟雾中，使其成为许多国家的一个重要公共卫生问题。目标：在这项研究中，我们的目的是测量严重森林火灾季节大城市中院外心脏骤停（OHCA）与森林火灾烟雾暴露之间的关联，并估计由于火灾烟雾导致的过量OHCA的数量。方法：我们通过对成年人的病例交叉研究，调查了颗粒物（PM）和其他空气污染物与OHCA之间的关系（>= 35岁）在澳大利亚的墨尔本。使用条件logistic回归模型来估计与暴露量四分位距（IQR）增加相关的OHCA发生率的百分比变化。从2006年7月到2007年6月，OHCA数据收集自维多利亚州救护车心脏骤停登记处。每小时的空气污染浓度和气象数据，从中央monitoringsite.Results：有2,046 OHCAs在我们的研究期间，假定心脏病因。在火灾季节的男性中，随着48小时滞后PM的IQR增加，观察到OHCA的增加更大，
Background: Millions of people can potentially be exposed to smoke from forest fires, making this an important public health problem in many countries. Objective: In this study we aimed to measure the association between out-of-hospital cardiac arrest (OHCA) and forest fire smoke exposures in a large city during a severe forest fire season, and estimate the number of excess OHCAs due to the fire smoke.Methods: We investigated the association between particulate matter (PM) and other air pollutants and OHCA using a case-crossover study of adults (>= 35 years of age) in Melbourne, Australia. Conditional logistic regression models were used to derive estimates of the percent change in the rate of OHCA associated with an interquartile range (IQR) increase in exposure. From July 2006 through June 2007, OHCA data were collected from the Victorian Ambulance Cardiac Arrest Registry. Hourly air pollution concentrations and meteorological data were obtained from a central monitoring site.Results: There were 2,046 OHCAs with presumed cardiac etiology during our study period. Among men during the fire season, greater increases in OHCA were observed with IQR increases in the 48-hr lagged PM with diameter