A motor signature of REM sleep behavior disorder
A motor signature of REM sleep behavior disorder
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DOI：
10.1002/mds.24044
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发表时间：
2012-03-01
影响因子：
8.6
通讯作者：
Arnulf, Isabelle
中科院分区：
文献类型：
--
作者：
Oudiette, Delphine;Leu-Semenescu, Smaranda;Arnulf, Isabelle
Background: The purpose of this study was to determine if there was a common pattern in movements during REM sleep behavior disorder (RBD).Methods: We blindly compared video-monitored movements during RBD (n = 136 clips) and wakefulness/ arousal (n = 53 clips) in patients with Parkinson's disease (n = 29) and without parkinsonism (idiopathic RBD, n = 31; narcolepsy, n = 5).Results: The scorers accurately guessed the sleep/ wake stage of 94% of video clips. Compared with wake movements, RBD movements were faster and more often repeated, jerky, and pseudohallucinatory, not self-centered, never associated with tremor, and rarely involved the environment in an appropriate manner. A specific posture of the hand (limp wrist with flexed digits) during grasping movements was evidenced during RBD in 48% of patients, reminiscent of hand-babbling in babies.Conclusions: These characteristics of movements were found in the 3 conditions (Parkinson's disease, idiopathic RBD, and primary narcolepsy), delineating a common motor signature of RBD. VC 2011 Movement Disorder Society
