Improved diagnosis and management of hyper- and hypothyroidism by timing the arterial sounds.
Improved diagnosis and management of hyper- and hypothyroidism by timing the arterial sounds.
复制标题
通过对动脉音进行定时，改善甲状腺功能亢进症和甲状腺功能减退症的诊断和治疗。
DOI：
10.1210/jcem-42-2-330
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发表时间：
1976
期刊：
影响因子：
--
通讯作者：
D. Rodbard
中科院分区：
文献类型：
--
作者：
R. Young;A. V. Van Herle;D. Rodbard
“脉搏记录”是一种非侵入性的动脉脉搏波轮廓计时方法，为甲状腺功能亢进和甲状腺功能减退患者的药物反应提供了客观的测量方法。QKd间隔，即，当血压计袖带处于舒张压（d）时，在肱动脉处从QRS波群（Q）开始到柯氏音（K）开始的间隔是QKd间隔。QKd通常为205 +/- 12 msec。甲亢时QKd间期可缩短至110 msec。在甲状腺功能减退症中，QKd间期可延长至320 msec。QKd的变化平行于临床状态和血清总T4和T3的变化，通过放射免疫测定法测量。QKd可作为甲亢抗甲状腺治疗和甲减患者甲状腺激素替代治疗的客观指导。
"Sphygmo-Recording," a non-invasive method for timing the arterial pulse wave contour provides an objective measure of responses to medication in patients with hyper- and hypothyroidism. The QKd interval, i.e., the interval from the onset of the QRS complex (Q) to the onset of the Korotkoff sounds (K) at the brachial artery when the sphygmomanometer cuff is at diastolic pressure (d) is the QKd interval. QKd is normally 205 +/- 12 msec. In the hyperthyroidism the QKd interval may be shortened to 110 msec. In hypothyroidism the QKd interval may be prolonged to 320 msec. Changes in QKd parallel changes in clinical status and serum total T4 and T3, measured by radioimmunoassay. QKd can be used as an objective guide to antithyroid therapy in hyperthyroidism and replacement therapy with thyroid hormone in hypothyroid individuals.