Synthesis and Characterization of Hydroxyapatite Nanoparticles using Sol-Gel Method
Synthesis and Characterization of Hydroxyapatite Nanoparticles using Sol-Gel Method
复制标题
溶胶-凝胶法羟基磷灰石纳米粒子的合成与表征
DOI：
10.18321/ectj71
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发表时间：
2010
影响因子：
0.5
通讯作者：
L. Manocha
中科院分区：
文献类型：
--
作者：
S. Manocha;Parth Joshi;B. Patel;L. Manocha
羟基磷灰石（HAp）是一种独特的材料，具有高的重金属吸附能力、高的离子交换能力、高的生物相容性、低的水溶性、在还原和氧化条件下的高稳定性、可用性和低成本。以四水硝酸钙[Ca（NO3）2 4 H2O]和五氧化二磷（P2 O 5）为原料，采用溶胶-凝胶法合成了羟基磷灰石纳米粒子。将五氧化二磷添加到硝酸钙四水合物中在搅拌的同时缓慢进行。添加后，将溶液老化10分钟以熟化。将沉淀物在80 °C下干燥过夜，并在550 °C下进一步热处理2小时。采用X射线衍射、红外光谱和热重分析对干燥和煅烧后的粉体进行了表征。使用透射电子显微镜研究了颗粒的尺寸和形态。经处理的粉末的TEM检查显示具有长度为20-50 nm的尺寸的多边形形态的颗粒。样品的FT-IR光谱证实了羟基磷灰石的形成。
Hydroxyapatite (HAp) is a unique material having high adsorption capacity of heavy metals, high ion exchange capacity, high biological compatibility, low water solubility, high stability under reducing and oxidizing conditions, availability and low cost. Hydroxyapatite nanoparticles have been synthesized by Sol-gel method using Calcium nitrate tetrahydrate [Ca(NO 3 ) 2 •4H 2 O] and Phosphorus pentaoxide (P 2 O 5 ) as starting reactants. The addition of Phosphorus pentaoxide to Calcium nitrate tetrahydrate was carried out slowly with simultaneous stirring. After addition, solution was aged for 10 minutes for maturation. The precipitate was dried at 80 °C overnight and further heat treated at 550 °C for 2 hours. The dried and calcined particles were characterized by X-ray diffractometry, Fourier transform infra-red spectroscopy and Thermo gravimetric analysis. The particle size and morphology were studied using transmission electron microscopy. TEM examination of the treated powders displayed particles of polygon morphology with dimensions 20-50 nm in length. The FT-IR spectra for sample confirmed the formation of hydroxyapatite.