An efficient intermolecular BINAM-copper(I) catalyzed Ullmann-type coupling of aryl iodides/bromides with aliphatic alcohols
An efficient intermolecular BINAM-copper(I) catalyzed Ullmann-type coupling of aryl iodides/bromides with aliphatic alcohols
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DOI：
10.1016/j.tetlet.2008.03.015
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发表时间：
2008-05-05
影响因子：
1.8
通讯作者：
Sekar, G.
中科院分区：
文献类型：
--
作者：
Naidu, Ajay B.;Sekar, G.
在催化量的易于获得的 BINAM-Cul 络合物存在下，通过乌尔曼型分子间偶联反应，由相应的芳基碘化物和脂肪醇合成各种烷基芳基醚。反应性较低的芳基溴也已被证明可以在相同的反应条件下与脂肪醇反应，从而在不增加反应温度和时间的情况下得到良好的烷基芳基醚收率。 (C) 2008 年，爱思唯尔有限公司出版。
A wide range of alkyl aryl ethers are synthesized from the corresponding aryl iodides and aliphatic alcohols through Ullmann-type intermolecular coupling reactions in the presence of a catalytic amount of easily available BINAM-Cul complex. Less reactive aryl bromides have also been shown to react with aliphatic alcohols under identical reaction conditions to give good yields of the alkyl aryl ethers without increasing the reaction temperature and time. (C) 2008 Published by Elsevier Ltd.