DIFFERENCES IN PERIODONTAL DISEASE-ASSOCIATED MICROORGANISMS OF SUBGINGIVAL PLAQUE IN PREPUBERTAL, PUBERTAL AND POSTPUBERTAL CHILDREN
DIFFERENCES IN PERIODONTAL DISEASE-ASSOCIATED MICROORGANISMS OF SUBGINGIVAL PLAQUE IN PREPUBERTAL, PUBERTAL AND POSTPUBERTAL CHILDREN
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DOI：
10.1902/jop.1987.58.4.219
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发表时间：
1987-04-01
影响因子：
4.3
通讯作者：
ROBINSON, PJ
中科院分区：
文献类型：
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作者：
WOJCICKI, CJ;HARPER, DS;ROBINSON, PJ
一般认为，正常青春期前的儿童不会患牙周炎，而且青春期前的儿童牙龈炎的严重程度通常低于青春期后的儿童。一种可能的解释是，与围产期疾病有关的细菌在青春期之前不能大量繁殖。Kornman和Loesche等人的研究表明，黑色类杆菌，尤其是B。中间肌，随着孕妇促性腺激素水平的增加而增加。Delaney和Kornman发现，在青春期，黑色拟杆菌的水平也有类似的增加。本研究涉及的文化和显微镜下的龈下菌斑植物群的青春期前，青春期周围和青春期后的儿童具有相似的Silness和Loe菌斑指数评分。通过腕关节X光片检查确认青春期。黑色素拟杆菌种群在青春期前儿童中非常低，而在青春期前后和青春期后儿童中要高得多。然而，B。中间肌仅在青春期周围斑块中占优势。在每个年龄段，总的能动细菌水平增加，但螺旋体水平高于2%，只观察到在青春期后组。这些结果支持了以前的研究者假设的激素水平和龈下菌斑中黑色色素类杆菌水平之间的关系，并表明龈下环境的差异深刻地影响了菌斑中可疑牙周病菌种的比例。
It is generally accepted that normal prepubertal children do not develop periodontitis, and that the severity of gingivitis in prepubertal children is usually less than that observed in children after puberty. One possible explanation is that the bacteria associated with peridontal diseases cannot become established in great numbers prior to puberty. Studies by Kornman and Loesche and others suggest that levels of black pigmented Bacteroides, especially B. intermedius, increase with increased levels of gonadotrophic hormones in pregnant women. Delaney and Kornman have found that there is a similar increase in levels of black pigmented Baceroides with puberty. The present study involved cultural and microscopic characterization of the subgingival plaque flora of prepubertal, circumpubertal and postpubertal children with similar Silness and Loe plaque index scores. Puberty was confirmed through examination of wrist radiographs. Populations of black pigmented Bacteroides were very low in prepubescent children and were much higher in circumpubertal and postpubertal children. However, B. intermedius predominated only in circumpubertal plaques. Levels of total motile bacteria increased at each age level, but levels of spirochetes above 2% were observed only in the postpubertal group. These results support those of previous investigators who postulated a relationship between hormone levels and black pigmented Bacteroides levels in subgingival plaque and suggest that differences in the subgingival environment profoundly influence the proportions of suspected periodontopathic species in plaque.