ATP-sensitive potassium channels are not expressed in brain microvessels.
ATP-sensitive potassium channels are not expressed in brain microvessels.
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ATP 敏感的钾通道在脑微血管中不表达。
DOI：
10.1016/0006-8993(93)91682-i
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发表时间：
1993
期刊：
影响因子：
2.9
通讯作者：
Harik,SI
中科院分区：
文献类型：
--
作者：
Sullivan,HC;Harik,SI
我们使用[3H]格列本脲结合来评估大鼠离体大脑微血管和大脑皮层中atp敏感的K+通道。我们发现，尽管格列本脲在大脑皮质膜中大量存在，但在大脑微血管中没有可测量的特异性格列本脲结合，这意味着在大脑微血管中不存在atp敏感的K+通道。
We used [3H]glibenclamide binding to assess ATP-sensitive K+channels in isolated cerebral microvessels and in the cerebral cortex of the rat. We found no measurable specific glibenclamide binding in cerebral microvessels despite its abundance in cerebral cortical membranes, implying that ATP-sensitive K+channels are not present in cerebral microvessels.