EMG-driven modeling approach to muscle force and joint load estimations: case study in knee osteoarthritis.
EMG-driven modeling approach to muscle force and joint load estimations: case study in knee osteoarthritis.
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DOI：
10.1002/jor.21544
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发表时间：
2012-03
影响因子：
2.8
通讯作者：
Manal, Kurt T.
中科院分区：
文献类型：
--
作者：
Kumar, Deepak;Rudolph, Katherine S.;Manal, Kurt T.
了解膝关节骨关节炎（OA）患者关节负荷的大小和模式非常重要，因为改变的负荷与疾病的发作和进展有关。我们使用肌电驱动的前向动力学模型来估计膝关节OA受试者和健康对照受试者行走过程中的关节负荷。使用Hill型肌肉模型，使用运动学、动力学和表面EMG数据来预测肌肉力。肌肉力量用于平衡额面力矩，以获得内侧和外侧髁载荷。将负荷标准化为体重（BW）和三次试验的平均值。与对照受试者相比，OA受试者的内侧载荷更大，外侧载荷更低。在对照受试者中，总负荷的75%至80%由内侧间室承担，而在OA受试者中为90%至95%。事实上，OA受试者在站立中期发生了完全的侧向卸载。健康受试者的载荷与膝关节内固定研究的数据一致。将来，该模型可用于分析各种干预措施的影响，以减少膝关节OA患者内侧间室的负荷。
It is important to know the magnitude and patterns of joint loading in people with knee osteoarthritis (OA), since altered loads are implicated in onset and progression of the disease. We used an EMG-driven forward dynamics model to estimate joint loads during walking in a subject with knee OA and a healthy control subject. Kinematic, kinetic, and surface EMG data were used to predict muscle forces using a Hill-type muscle model. The muscle forces were used to balance the frontal plane moment to obtain medial and lateral condylar loads. Loads were normalized to body weight (BWs) and the mean of three trials taken. The OA subject had greater medial and lower lateral loads compared to the control subject. 75 to 80% of the total load was borne on the medial compartment in the control subject, compared to 90 to 95% in the OA subject. In fact, complete lateral unloading occurred during midstance for the OA subject. Loading for the healthy subject was consistent with the data from instrumented knee studies. In the future, the model can be used to analyze the impact of various interventions to reduce the loads on the medial compartment in people with knee OA.
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