Relationship between insomnia with alcohol drinking before sleep (Ne-Zake) or in the morning (Mukae-Zake) among Japanese farmers
Relationship between insomnia with alcohol drinking before sleep (Ne-Zake) or in the morning (Mukae-Zake) among Japanese farmers
复制标题
日本农民失眠与睡前饮酒 (Ne-Zake) 或早晨饮酒 (Mukae-Zake) 的关系
DOI：
10.1016/j.alcohol.2020.11.005
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发表时间：
2021
期刊：
影响因子：
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通讯作者：
Sato,R,Hisamatsu,T,Tsumura,H,Fukuda,M,Taniguchi,K,Takeshita,H,Kanda,H.
中科院分区：
文献类型：
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作者：
髙岡 昂太 ; 坂本 次郎 ; 橋本 笑穂 ; 北條 大樹 ; 古川 結唯 ; 鈴木 聡 ; 山本恒雄;山本哲也;Sato,R,Hisamatsu,T,Tsumura,H,Fukuda,M,Taniguchi,K,Takeshita,H,Kanda,H.
“ne - zake”是指睡前喝酒，帮助入睡和睡得好；“Mukae-Zake”是指早上喝酒，用来“镇静”或“治疗宿醉”。目的探讨日本健康中年农民失眠与Ne-Zake和Mukae-Zake的关系。方法对746名参与者（平均年龄59.5岁，女性占25.9%）进行横断面研究，采用自填问卷对Ne-Zake和Mukae-Zake进行定义。失眠定义为雅典失眠量表日本版≥6或前一年服用安眠药。采用Logistic回归计算与Ne-Zake和Mukae-Zake相关的失眠的比值比（OR），调整性别、年龄、睡眠相关障碍的存在、饮酒频率和每次饮酒的数量。结果分别有174例（23.3%）、140例（18.8%）和37例（5.0%）出现失眠、Ne-Zake和Mukae-Zake。在调整了人口统计学和混杂因素后，与没有Ne-Zake的患者相比，Ne-Zake患者的失眠症患病率明显更高（OR为2.00[95%可信区间，1.27-3.16]）。Mukae-Zake也与男性较高的失眠症患病率独立相关（OR为3.26[1.55-6.87]）。与既没有Ne-Zake也没有Mukae-Zake的参与者相比，同时患有Ne-Zake和Mukae-Zake的参与者与失眠的相关性非常显著（OR为4.77[2.01-11.3]）。此外，对于失眠，Mukae-Zake的相关性比Ne-Zake更明显（OR为4.09,95% CI 1.14-14.7,p= 0.031； OR为1.81,95% CI 1.08-3.06,p= 0.026）。结论在日本农民中，ne - zake和Mukae-Zake与失眠相关，与饮酒量和饮酒频率无关。这一发现可以用于对失眠症患者进行分层，不仅可以改善睡眠卫生，还可以通过告知普通人群酒精对睡眠有负面影响来预防酒精依赖，这与流行的看法相反。
BackgroundNe-Zake is the drinking of alcohol before sleeping for helping to fall asleep and sleep well, and Mukae-Zake is the drinking of alcohol in the morning for “calming down” or “curing hangovers”.ObjectiveWe sought to examine the relationship of insomnia with Ne-Zake and Mukae-Zake among healthy middle-aged Japanese farmers.MethodsIn a cross-sectional study of 746 participants (mean age, 59.5 years; women, 25.9%), Ne-Zake and Mukae-Zake were defined based on a self-administered questionnaire. Insomnia was defined as the Athens Insomnia Scale Japanese version ≥6 or usage of sleeping pills in the previous year. Logistic regression was used to calculate odds ratio (OR) of insomnia related to Ne-Zake and Mukae-Zake adjusting for sex, age, presence of sleep-related disorders, frequency of alcohol consumption, and quantity of alcohol consumed per one occasion.ResultsWe observed insomnia, Ne-Zake, and Mukae-Zake in 174 (23.3%), 140 (18.8%), and 37 (5.0%) participants, respectively. After adjustment for demographic and confounding factors, participants with Ne-Zake had a significantly higher prevalence of insomnia (OR 2.00 [95% confidence interval, 1.27–3.16]), compared to those without Ne-Zake. Mukae-Zake was also independently associated with a higher prevalence of insomnia among men (OR 3.26 [1.55–6.87]). Participants with both Ne-Zake and Mukae-Zake had a highly significant association with insomnia (OR 4.77 [2.01–11.3]) than those with neither Ne-Zake nor Mukae-Zake. Additionally, for insomnia, the association of Mukae-Zake was more pronounced than that of Ne-Zake (OR 4.09, 95% CI 1.14–14.7,p= 0.031; and OR 1.81, 95% CI 1.08–3.06,p= 0.026, respectively).ConclusionNe-Zake and Mukae-Zake were associated with insomnia independent of the quantity and frequency of alcohol consumption among Japanese farmers. This finding can be used for stratifying individuals with insomnia not only to improve sleep hygiene but also to prevent alcohol dependence by informing the general population that alcohol has a negative effect on sleep, contrary to popular beliefs.