SEROLOGICAL RELATIONSHIPS BETWEEN DIFFERENT STRAINS OF VESICULAR STOMATIS VIRUS
SEROLOGICAL RELATIONSHIPS BETWEEN DIFFERENT STRAINS OF VESICULAR STOMATIS VIRUS
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DOI：
10.1099/0022-1317-16-3-391
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发表时间：
1972-01-01
影响因子：
3.8
通讯作者：
BROWN, F
中科院分区：
文献类型：
--
作者：
CARTWRIGHT, B;BROWN, F
The five vesicular stomatitis viruses Indiana, New Jersey, Cocal, Argentina and Brazil have been examined for cross-relationships by complement fixing and neutralization tests. With the exception of the Cocal and Argentina strains, intact virus particles showed little cross-reaction in either test. However, the infective skeleton-like structure produced by uncoating the virus with Tween-ether or Nonidet, and the infective ribonucleoprotein (RNP) produced by deoxycholate disruption of the virus, were neutralized by either homo- or heterotypic antisera and showed considerable cross-reactivity in the complement fixation test. Experiments with the isolated sub-units of the virus indicated that the major part of the cross-reactivity was associated with the RNP. The morphologically similar Piry and Chandipura viruses appeared to be unrelated to the vesicular stomatitis group in both complement fixation and neutralization tests.
