Comparative effectiveness of oral pharmacologic interventions for knee osteoarthritis: A network meta-analysis
Comparative effectiveness of oral pharmacologic interventions for knee osteoarthritis: A network meta-analysis
复制标题
DOI：
10.1080/14397595.2018.1439694
复制
发表时间：
2018-01-01
影响因子：
2.2
通讯作者：
Sung, Yoon-Kyoung
中科院分区：
文献类型：
--
作者：
Jung, Sun-Young;Jang, Eun Jin;Sung, Yoon-Kyoung
目的：探讨口服药物干预治疗膝关节OA.Methods的相对疗效：使用MEDLINE，EMBASE和科克伦对照试验数据库的中央注册进行系统的文献综述，以确定在膝关节OA患者进行的试验，至少6周的后续行动。使用贝叶斯随机效应网络荟萃分析估计治疗组之间西安大略和麦克马斯特大学关节炎指数（WOMAC）疼痛从基线至第6周变化的标准化平均差异。基线疼痛状态的亚组分析（高，疼痛评分60 mm;低，疼痛评分
Objectives: To explore the relative efficacy of oral pharmacologic interventions in the treatment of knee OA.Methods: A systematic literature review was conducted using the MEDLINE, EMBASE, and Cochrane Central Register of Controlled Trials databases to identify trials conducted in patients with knee OA with a minimum 6 weeks of follow-up. The standardized mean differences of the change from baseline to week 6 in Western Ontario and McMaster Universities Arthritis Index (WOMAC) pain between the treatment groups were estimated using Bayesian random-effects network meta-analyses. Subgroup analyses of baseline pain status (high, pain score 60mm; low, pain score