Thoracolumbar Scoliosis Due to Cryptococcal Osteomyelitis: A Case Report and Review of the Literature.

Thoracolumbar Scoliosis Due to Cryptococcal Osteomyelitis: A Case Report and Review of the Literature.
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隐球菌性骨髓炎胸腰椎侧凸一例报告并文献复习

DOI:
10.1097/md.0000000000002613
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发表时间:
2016-02
期刊:
影响因子:
1.6
通讯作者:
Weng X
Weng X
中科院分区:
医学4区
文献类型:
--
作者:
Li Z;Liang J;Shen J;Qiu G;Weng X

文献摘要

被引文献

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新型隐球菌引起免疫功能低下患者机会性感染,脊椎骨髓炎是一个非常罕见的参与。本研究报告一位胸腰椎侧凸合并隐球菌性骨髓炎的病例。给予抗隐球菌药物的药物干预和免疫性溶血性贫血的药物管理。在最初的急性稳定后,她于2008年10月29日接受了脊柱清创和融合术。她最终从该事件中完全恢复,在随后的临床随访中没有随后的机械不稳定或神经功能缺损。据我们所知,目前还没有报道脊髓隐球菌性骨髓炎沿着免疫性溶血性贫血。我们建议一个全面的算法诊断脊椎隐球菌性骨髓炎。
Cryptococcus neoformans causes opportunistic infections in immunocompromised patients, with vertebral osteomyelitis being a very rare involvement. This study is to present a case of thoracolumbar scoliosis occurring in the setting of cryptococcal osteomyelitis. Pharmacological intervention with anticryptococcal medicine and medical management of immune hemolytic anemia were administered. After initial acute stabilization, she underwent spinal debridement and fusion on October 29, 2008. She eventually recovered fully from this episode with no subsequent mechanical instability or neurological deficits on subsequent clinic follow-ups. To the best of our knowledge, there have been no reports describing the onset of spinal cryptococcal osteomyelitis along with immune hemolytic anemia. We suggest a comprehensive algorithm for the diagnosis of vertebral cryptococcal osteomyelitis.