A randomized clinical multicentre trial comparing enamel matrix derivative and membrane treatment of buccal class II furcation involvement in mandibular molars. Part III: patient factors and treatment outcome
A randomized clinical multicentre trial comparing enamel matrix derivative and membrane treatment of buccal class II furcation involvement in mandibular molars. Part III: patient factors and treatment outcome
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DOI：
10.1111/j.1600-051x.2006.00947.x
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发表时间：
2006-08-01
影响因子：
6.7
通讯作者：
Boedeker, Rolf-Hasso
中科院分区：
文献类型：
--
作者：
Hoffmann, Thomas;Richter, Steffen;Boedeker, Rolf-Hasso
目的：评估患者因素对颊下颌骨II类根分叉缺损再生治疗结果的影响。材料和方法：51例患者被招募。在意向治疗人群中，21例患者被分配到左侧釉基质蛋白衍生物（EMD）和右侧引导组织再生（GTR）治疗序列中，27例患者被分配到左侧GTR和右侧EMD治疗序列中。评估的患者因素包括：吸烟、年龄、性别、高血压和口腔卫生状况。结果参数包括：（a）最深点处缺损的水平深度（B）从分叉穹隆到缺损骨嵴的距离，（c）支架到缺损底部的距离，（d）囊袋深度和（e）分叉中部的附着水平。在54岁及以上的患者、男性、非吸烟者和卫生状况“差”的患者中，EMD治疗部位的参数d（年龄）、B的平均降低值显著更高（性别，卫生）a（吸烟，卫生）相比，与GTR治疗的网站。结论：这些数据提供了一个可能的影响，颊下颌II类分叉缺损的再生治疗的结果患者因素的指示。
Objectives: Evaluation of effects of patient factors on the outcome of regenerative treatment of buccal mandibular class II furcation defects.Materials and Methods: Fifty-one patients were recruited. In the intention-to-treat population 21 patients were allocated into the sequence left treatment with enamel matrix protein derivative (EMD) and right guided tissue regeneration (GTR) and 27 in the sequence left GTR and right EMD. Evaluated patient factors were: smoking, age, gender, hypertension and oral hygiene status. Outcome parameters included change of: (a) horizontal depth of the defect at the deepest point (b) distance from the fornix of the furcation to bone crest of the defect, (c) distance from stent to the bottom of the defect, (d) pocket depth and (e) attachment level at the middle of the furcation.Results: In patients 54 years of age and older, in males, in non-smokers and in patients with "poor" hygiene EMD-treated sites showed a significant higher mean reduction of the parameters d (age), b (gender, hygiene) a (smoking, hygiene) when compared with sites treated with GTR.Conclusions: These data provided an indication of a possible effect of patient factors on the outcome of regenerative treatment of buccal mandibular class II furcation defects.