Executive dysfunction is a significant predictor of poor quality of life in children with epilepsy
Executive dysfunction is a significant predictor of poor quality of life in children with epilepsy
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DOI：
10.1111/j.1528-1167.2006.00816.x
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发表时间：
2006-11-01
期刊：
影响因子：
5.6
通讯作者：
Eyrl, Kim L.
中科院分区：
文献类型：
--
作者：
Sherman, Elisabeth M. S.;Slick, Daniel J.;Eyrl, Kim L.
目的：基于先前的研究表明注意缺陷/多动障碍儿童的健康相关生活质量（HRQOL）较差，我们研究了（1）癫痫儿童的执行功能缺陷是否与HRQOL较差有关，（2）与HRQOL的已知预测因子（如神经因素）相比，这些变量的重要性如何，以及（3）执行功能障碍的临床水平损害在多大程度上使儿童易患低HRQOL。数据包括执行功能行为评定量表（BRIEF）和HRQOL量表的评分（儿童疾病量表[ICI]和海牙癫痫限制量表[HARCES]的影响）（平均年龄= 11.9岁，标准差= 3.6）。结果：BRIEF与ICI总分和分项得分域（儿童、父母、家庭和治疗）之间的相关性通常是显著和中度的（例如，r >= 0.30，p
Purpose: Based on prior research indicating poor health-related quality of life (HRQOL) in children with attention-deficit/hyperactivity disorder, we investigated (1) whether executive functioning deficits were related to poor HRQOL in children with epilepsy, (2) how important these variables were in comparison to known predictors of HRQOL such as neurological factors, and (3) the extent to which clinical-level impairments in executive dysfunction predispose children to low HRQOL.Method: Data included scores on the Behavior Rating Inventory of Executive Function (BRIEF) and HRQOL scales (The Impact of Childhood Illness Scale [ICI] and Hague Restrictions in Epilepsy Scale [HARCES]) for 121 children (mean age = 11.9, SD = 3.6) from a tertiary center serving children with severe epilepsy.Results: Correlations between the BRIEF and ICI total and subscore domains (child, parent, family, and treatment) were generally significant and moderate (e.g., r >= 0.30, p