Occurrence of riboflavinyl glucoside in rat urine.

Occurrence of riboflavinyl glucoside in rat urine.
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大鼠尿液中存在核黄素葡萄糖苷。

DOI:
10.3177/jnsv.29.515
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发表时间:
1983
影响因子:
1.6
通讯作者:
K. Yagi
K. Yagi
中科院分区:
医学4区
文献类型:
--
作者:
H. Ohkawa;N. Ohishi;K. Yagi

文献摘要

被引文献

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为了研究核黄素的代谢,给大鼠灌胃[2-14C]-核黄素。用纸层析法和硅胶薄层层析法分离给药后24小时的尿液。在放射性代谢产物中,核黄素葡萄糖苷与7-羧基光色素和8-羧基光色素一起被发现。核黄素葡萄糖苷的放射性约占24小时尿中总放射性的6%。
To investigate the metabolism of riboflavin, [2-14 C]-riboflavin was administered orally to a rat. The urine pooled for 24h after administration was fractionated by paper and silica gel thin layer chromatographies using various solvent systems. Among the radioactive metabolites, riboflavinyl glucoside was found along with 7-carboxy lumichrome and 8-carboxy lumichrome. The radioactivity of riboflavinyl glucoside comprised about 6% of the total radioactivity excreted in the urine during 24h.