A Review of the Relationship of Atrial Fibrillation and Acute Coronary Syndrome.
A Review of the Relationship of Atrial Fibrillation and Acute Coronary Syndrome.
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DOI：
10.1007/s40138-016-0105-2
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发表时间：
2016-09
影响因子：
0.7
通讯作者：
Raitt M
中科院分区：
文献类型：
--
作者：
Kea B;Alligood T;Manning V;Raitt M
心房颤动（AF）是临床医生最常见的心律失常。临床决策的重点是降低AF患者的缺血性卒中风险;然而，AF也与急性冠状动脉综合征（ACS）风险增加相关。与窦性心律（SR）的ACS患者相比，ACS合并AF患者接受适当治疗的可能性更低，更可能发生不良结局。临床医生可能能够根据临床特征对AF发生风险增加的ACS患者进行分层。支持AF患者预防ACS或ACS患者预防AF的特定治疗选择的证据有限，但有一些证据表明这些人群中口服抗凝剂方案的效果不同。AF与ACS全谱的关系的调查没有得到很好的描述，应该是未来研究的重点。
Atrial fibrillation (AF) is the most common arrhythmia encountered by clinicians. Clinical decision-making focuses on reducing ischemic stroke risk in AF patients; however, AF is also associated with an increased risk of acute coronary syndromes (ACS). Patients with ACS and concurrent AF are less likely to receive appropriate therapies and more likely to experience adverse outcomes than ACS patients in sinus rhythm (SR). Clinicians may be able to stratify ACS patients at increased risk of AF development based on clinical characteristics. Evidence supporting specific therapeutic options for prevention of ACS in AF patients or for prevention of AF in ACS patients is limited, however there is some evidence of differing effects among oral anticoagulant regimens in these populations. Investigations of the relationship of AF with the full spectrum of ACS are not well described and should be the focus of future research.