Dietary sesame reduces serum cholesterol and enhances antioxidant capacity in hypercholesterolemia
Dietary sesame reduces serum cholesterol and enhances antioxidant capacity in hypercholesterolemia
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DOI：
10.1016/j.nutres.2005.05.007
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发表时间：
2005-06-01
影响因子：
4.5
通讯作者：
Tsai, CM
中科院分区：
文献类型：
--
作者：
Chen, PR;Chien, KL;Tsai, CM
目的：观察芝麻对21例高血压病患者的降血脂和增强抗氧化能力的作用。受试者被指示在开始实验饮食之前食用他们的常规饮食2周。实验饮食与40克烤芝麻消耗4周，然后再为4周的常规饮食。在第0、4和8周测定体重和空腹血液。结果表明，日粮中添加芝麻能显著降低血清总胆固醇和低密度脂蛋白胆固醇水平。红细胞溶血的时间和LDL氧化的滞后期显着增加芝麻摄入。含有芝麻的饮食略微降低了LDL中硫代巴比妥酸反应物质的水平。当患者恢复正常饮食时，芝麻的有益作用消失了。在这项研究中，芝麻似乎对高胆固醇血症患者的血脂和抗氧化能力产生有益的影响。(c)2005年爱思唯尔公司All rights reserved.
The purpose of the study was to investigate the effects of sesame on lowering serum lipids and enhancing antioxidant capacity in 21 hyperlipidemic patients. Subjects were instructed to consume their regular diet for 2 weeks before starting the experimental diet. The experimental diet with 40 g roasted sesame was consumed for 4 weeks and the regular diet followed for another 4 weeks. Body weights and fasting blood were determined at weeks 0, 4, and 8. The results showed that the diet with sesame significantly decreased the levels of serum total cholesterol and low-density lipoprotein (LDL) cholesterol. The time for erythrocyte hemolysis and the lag phase of LDL oxidation were significantly increased by sesame ingestion. A diet containing sesame slightly reduced the levels of thiobarbituric acid-reactive substances in LDL. The beneficial effects of sesame disappeared when patients returned to their regular diets. Sesame in this study appeared to exert beneficial effects on serum lipids and to improve antioxidant capacity in hypercholesterolemic patients. (c) 2005 Elsevier Inc. All rights reserved.