Trisomy 13 syndrome.
Trisomy 13 syndrome.
复制标题
13 三体综合征。
DOI：
10.1097/mao.0b013e31817dad43
复制
发表时间：
2008
期刊：
影响因子：
--
通讯作者：
Paparella,MichaelM
中科院分区：
文献类型：
--
作者：
Fukushima,Hisaki;Harada,Tamotsu;Morita,Norimasa;Paparella,MichaelM
13三体综合征发生在大约1/5000的活产婴儿中，伴有多种先天性异常。最常见的耳鼻喉科表现是呼吸暂停、唇腭裂、外鼻发育不全、耳低位、外耳道狭窄以及导致耳聋的中耳和内耳异常。据我们所知，已经报道了20多例这种综合征的颞骨研究（1，2）。
Trisomy 13 syndrome occurs in approximately 1 in 5,000 live births with multiple congenital anomalies. The most common otolaryngologic findings are apneic spells, cleft plate and lip, agenesis of the nasus externus, low-set ears, stenotic external ear canals, and middle and inner ear anomalies causing deafness. To our knowledge, more than 20 cases of temporal bone studies of this syndrome have been reported (1, 2).