Congenital posterior choanal atresia.
Congenital posterior choanal atresia.
复制标题
先天性后鼻孔闭锁。
DOI：
10.1542/peds.76.3.429
复制
发表时间：
1985
期刊：
影响因子：
8
通讯作者：
M. J. Jurkiewicz
中科院分区：
文献类型：
--
作者：
R. S. Stahl;M. J. Jurkiewicz
尽管在两个多世纪前就有了描述，但先天性后鼻孔闭锁仍然是一种尚未建立最佳治疗方法的疾病。在一项为期 14 年期间对 29 例先天性后鼻孔闭锁病例进行的研究中，诊断出 14 名男性和 15 名女性患者，而通常报道的男女比例为 2:1。该系列对 16 名接受手术治疗的患者进行了 32 次手术。随访 2 个月至 6.5 年期间，经腭手术和经鼻手术这两种手术治疗的复发率分别为 66% 和 73%。在之前的研究中，面部生长障碍已被证明是由成长中的儿童经腭切除术引起的，而经鼻技术已被指控为严重神经系统并发症的原因。由于本系列中的 20 例鼻内手术没有造成重大发病率，因此提倡早期连续鼻内穿孔作为建立和维持鼻气道通畅的一种手段，直到面部生长更加完全时可以进行最终的经鼻修复。
Although described more than two centuries ago, congenital choanal atresia remains an entity for which optimum treatment is not yet established. In a study of 29 cases of cogenital choanal atresia during a 14-year period, 14 male and 15 female patients were diagnosed, in contrast with the 2:1 female-male ratio usually reported. Thirty-two operative procedures were performed on 16 surgically treated patients in the series. The two classes of surgical treatment, transpalatal and transnasal techniques, were marked by 66% and 73% recurrence rates, respectively, from 2 months to 6.5 years of follow-up. In previous studies, facial growth disturbances have been shown to result from transpalatal resection in the growing child, whereas transnasal techniques have been indicted as a cause of serious neurologic complications. Because no major morbidity resulted from 20 endonasal procedures in this series, early serial endonasal perforation is advocated as a means of establishing and maintaining a patent nasal airway until definitive transnasal repair can be performed when facial growth is more complete.