The proBAM and proBed standard formats: enabling a seamless integration of genomics and proteomics data
The proBAM and proBed standard formats: enabling a seamless integration of genomics and proteomics data
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proBAM 和 proBed 标准格式:实现基因组学和蛋白质组学数据的无缝集成
DOI:
10.1101/152579
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发表时间:
2017
期刊:
影响因子:
--
通讯作者:
Menschaert G
中科院分区:
文献类型:
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作者:
Menschaert G
On behalf of The Human Proteome Organization (HUPO) Proteomics Standards Initiative, we introduce here two novel standard data formats, proBAM and proBed, that have been developed to address the current challenges of integrating mass spectrometry-based proteomics data with genomics and transcriptomics information in proteogenomics studies. proBAM and proBed are adaptations of the well-defined, widely used file formats SAM/BAM and BED, respectively, and both have been extended to meet the specific requirements entailed by proteomics data. Therefore, existing popular genomics tools such as SAMtools and Bedtools, and several widely used genome browsers, can already be used to manipulate and visualize these formats “out-of-the-box.” We also highlight that a number of specific additional software tools, properly supporting the proteomics information available in these formats, are now available providing functionalities such as file generation, file conversion, and data analysis. All the related documentation, including the detailed file format specifications and example files, are accessible at http://www.psidev.info/probam and at http://www.psidev.info/probed .
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DOI:
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发表时间:
--
期刊:
影响因子:
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作者:
通讯作者:
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影响因子:
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