How common is postpartum thyroiditis? A methodologic overview of the literature.

How common is postpartum thyroiditis? A methodologic overview of the literature.
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产后甲状腺炎有多常见?

DOI:
10.1001/archinte.1990.00390190063008
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发表时间:
1990
影响因子:
--
通讯作者:
H. Gerstein
H. Gerstein
中科院分区:
--
文献类型:
--
作者:
H. Gerstein

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据报道,一般人群中产后甲状腺炎(PPT)的发病率范围为1.9%至16.7%,具体取决于研究。为了确定偏倚是否可能在这些差异很大的估计值的产生中发挥了作用,一组方法学标准被应用于已发表的关于PPT流行病学的原始研究。通过这些方法学过滤器的文章报告的PPT发生率范围较窄,介于3.7%和5.9%之间。对这些文章的再分析证实,产后前3个月甲状腺毒症的发生率高于甲状腺功能减退症,并且阳性抗微粒体抗体滴度与产后甲状腺功能障碍密切相关(比值比,86.6; 95%置信区间,45.9至163.2)。这篇文章表明,产后抑郁症是一种常见的条件,发生在产后期间。产后妇女产后出血发生率的最佳估计值为4.9%。
The incidence of postpartum thyroiditis (PPT) in the general population has been reported to range from 1.9% to 16.7%, depending on the study. To determine whether bias may have played a role in the generation of these widely varying estimates, a set of methodologic criteria were applied to the published original research dealing with the epidemiology of PPT. The articles that passed these methodologic filters reported a narrow range of incidences of PPT, varying between 3.7% and 5.9%. Reanalysis of these articles confirmed that thyrotoxicosis occurred more frequently in the first 3 months post partum than did hypothyroidism, and that a positive antimicrosomal antibody titer was strongly associated with postpartum thyroid dysfunction (odds ratio, 86.6; 95% confidence interval, 45.9 to 163.2). This article suggests that PPT is a common condition that occurs in the postpartum period. The best estimate of the incidence of PPT in an unselected cohort of postpartum women is 4.9%.
DOI: 10.7326/0003-4819-107-2-224
发表时间: 1987-08-01
影响因子: 39.2
作者:
LABBE, KA;DETSKY, AS;OROURKE, K
通讯作者: OROURKE, K