Sigma factors for cyanobacterial transcription.
Sigma factors for cyanobacterial transcription.
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DOI：
10.4137/grsb.s2090
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发表时间：
2009-04-22
期刊：
影响因子：
--
通讯作者：
Asayama M
中科院分区：
文献类型：
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作者：
Imamura S;Asayama M
蓝藻是一种可以进行光合作用的微生物，可以作为分析基因表达的模型。基因的表达包括转录和翻译。转录由RNA聚合酶（RNAP）全酶完成，全酶包括一个核心酶和一个sigma （σ）因子，该因子赋予启动子选择性。本文基于前人的研究，对蓝藻σ因子（及RNAP核心亚基）的独特结构、表达和功能进行了综述。还讨论了σ因子识别的启动子类型在转录调控中的作用。
Cyanobacteria are photosynthesizing microorganisms that can be used as a model for analyzing gene expression. The expression of genes involves transcription and translation. Transcription is performed by the RNA polymerase (RNAP) holoenzyme, comprising a core enzyme and a sigma (σ) factor which confers promoter selectivity. The unique structure, expression, and function of cyanobacterial σ factors (and RNAP core subunits) are summarized here based on studies, reported previously. The types of promoter recognized by the σ factors are also discussed with regard to transcriptional regulation.