Thought and Language Index: an instrument for assessing thought and language in schizophrenia
Thought and Language Index: an instrument for assessing thought and language in schizophrenia
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DOI：
10.1192/bjp.181.4.326
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发表时间：
2002-10-01
影响因子：
10.5
通讯作者：
Weg, R
中科院分区：
文献类型：
--
作者：
Liddle, PF;Ngan, ETC;Weg, R
背景微妙的正式思维障碍是难以量化的。目的评估一种新的评估工具--思维和语言指数（Thought and Language Index，TLI）的信度、敏感度和因子结构，并确定健康个体言语中可检测到的微小畸变是否与精神分裂症特征性的更严重的形式思维障碍有关。由五位评审员评分。对87例患者的TLI评分进行因子分析，并对匹配的患者和对照组的TLI评分进行比较。因子分析确定了三组近似正交的疾病。在健康参与者和精神分裂症患者中观察到轻度言语畸变。轻度畸变的患病率与明确的正式思维disorders.Conclusions的患病率TLI是可靠的，能够检测细微的疾病。健康人言语中出现的一些轻度畸变似乎是精神分裂症特征性语言障碍的减弱形式。
Background Subtle formal thought disorders are difficult to quantify. Their relationship to florid thought disorder is unknown.Aims To assess the interrater reliability, sensitivity and factor structure of a new assessment instrument, the Thought and Language Index (TLI), and to determine if minor aberrations detectable in the speech of healthy individuals are related to the more severe formal thought disorders characteristic of schizophrenia.Method Interrater reliability was evaluated by determining the intraclass correlation for the ratings by five assessors. Factor analysis of the TLI scores of 87 patients was performed, and TLI scores in matched patients and controls were compared.Results The intraclass correlation was good for individual TLI items, and excellent for sub-scale scores. Factor analysis identified three groups of approximately orthogonal disorders. Mild speech aberrations were observed in healthy participants and in patients with schizophrenia. The prevalence of mild aberrations was correlated with the prevalence of definite formal thought disorders.Conclusions The TLI is reliable and capable of detecting subtle disorders. Some mild aberrations occurring in the speech of healthy individuals appear to be attenuated forms of the florid disorders characteristic of schizophrenia.Declaration of interest None.