HIPPOCAMPUS, AMYGDALA, AND MEMORY DEFICITS IN RATS
HIPPOCAMPUS, AMYGDALA, AND MEMORY DEFICITS IN RATS
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DOI：
10.1016/0166-4328(90)90072-m
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发表时间：
1990-02-12
影响因子：
2.7
通讯作者：
MCDONALD, RJ
中科院分区：
文献类型：
--
作者：
SUTHERLAND, RJ;MCDONALD, RJ
本研究通过五个实验比较了海马结构和杏仁核在记忆过程中的作用。海马结构或杏仁核损伤的大鼠的表现进行了检查，在测试中的视觉和嗅觉不匹配的样本与熟悉的项目，跨通道协会，味觉新恐惧症，地形记忆，自主条件的背景下，和神经元的歧视。两种病变均不影响与样本不匹配的性能。一个完整的海马结构，但不是杏仁核，是必要的视觉和嗅觉，地形记忆，条件反射的背景下，和神经辨别学习之间的跨模式的关联。杏仁核损伤扰乱了味觉新恐惧症，并可能损害了学习听觉线索和食物奖励之间的联系。
Five experiments were conducted to compare the contribution of the hippocampal formation and amygdala to mnemonic processes. The performance of rats with damage to the hippocampal formation or amygdala was examined in tests of visual and olfactory non-matching-to-sample with familiar items, cross-modal association, gustatory neophobia, topographical memory, autonomic conditioning to context, and configural discrimination. Neither lesion affects non-matching-to-sample performance. An intact hippocampal formation, but not amygdala, is necessary for cross-modal association between vision and olfaction, topographical memory, conditioning to context, and configural discrimination learning. Amygdala damage disrupted gustatory neophobia and may have impaired learning an association between an auditory cue and food reward.