Isolated acalculia due to left parietal lesion.

Isolated acalculia due to left parietal lesion.
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DOI:
10.1001/archneur.1994.00540150084021
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发表时间:
1994-03
影响因子:
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通讯作者:
Y. Takayama;M. Sugishita;I. Akiguchi;J. Kimura
Y. Takayama;M. Sugishita;I. Akiguchi;J. Kimura
中科院分区:
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文献类型:
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作者:
Y. Takayama;M. Sugishita;I. Akiguchi;J. Kimura

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目的探讨左顶叶病变所致孤立性计算障碍的特点和定位。设计案例系列。设置三级护理医院。患者和其他参与者介绍了3名因左顶叶中风而导致孤立计算障碍的患者。16名年龄和文化程度的志愿者为对照组。结果:进行神经心理测试,包括一系列失算测试和韦氏成人智力量表,以及磁共振成像。结果3例患者在多个步骤同时进行的过程中出现计算错误。患者在数字手术中均未出现失语成分。他们了解计算的基本过程。他们在检索表值方面没有遇到什么困难。患者在对齐算术问题或分配和保持位置保持值方面没有障碍。他们没有表现出对计算问题的即时记忆不足。重叠病变位于左侧顶叶内沟。结论左侧顶内沟区域是孤立性顶叶失算的关键部位。孤立性失算的特征表明,这是由于用于计算的工作记忆被破坏所致。
OBJECTIVE To clarify the characteristics and the localization of isolated calculation disturbances due to left parietal lesions. DESIGN Case series. SETTING Tertiary care hospital. PATIENTS AND OTHER PARTICIPANTS Three referred patients with isolated calculation disturbances due to stroke in the left parietal region. Sixteen volunteers for age and education constituted the control group. OUTCOME MEASURES Neuropsychological tests, including a battery of tests for acalculia and the Wechsler Adult Intelligence Scale, and magnetic resonance imaging were performed. RESULTS Three patients made calculation errors in the process where a number of steps were carried out simultaneously. The patients showed no aphasic components in number operations. They understood the basic processes of calculation. They showed little difficulty in the retrieval of table values. The patients had no impairment in aligning arithmetic problems or in assigning and maintaining place-holding values. They did not show any deficit of immediate memory for calculation problems. Overlapping lesions were located along the left intraparietal sulcus. CONCLUSION The area lying along the left intraparietal sulcus is critical for isolated parietal acalculia. The profile of isolated acalculia suggests that it results from the disruption of the working memory for calculation.