The role of Nicorandil in non-healing surgical wounds.
The role of Nicorandil in non-healing surgical wounds.
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DOI：
10.1308/147870810x12699662981113
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发表时间：
2010-09-01
影响因子：
1.4
通讯作者：
Harding, K J
中科院分区：
文献类型：
--
作者：
Riddell, A D;Minhas, U;Harding, K J
我们报告了两名手术伤口不愈合的患者，在停止尼可地尔治疗后愈合。一旦排除其他炎症和恶性原因，尼可地尔应被视为伤口不愈合或溃疡的病因。这可以避免高危患者进行手术，也可以减少因不愈合伤口而接受手术的患者的并发症。由于尼可地尔用于患有严重冠状动脉疾病的患者，建议在停止或调整剂量之前征求心脏病专家的建议。
We report two patients with non-healing surgical wounds, which healed after the withdrawal of Nicorandil therapy. Nicorandil should be recognised as an aetiological factor for non-healing wounds or ulcers once other inflammatory and malignant causes have been excluded. This may avoid surgery for high-risk patients and may also reduce complications for patients who undergo surgery for non-healing wounds. As Nicorandil is used in patients with severe coronary artery disease, it is recommended that the advice of a cardiologist is sought prior to cessation or adjustment to its dose.